Search results for "pulmonary metastasis"
showing 3 items of 3 documents
Metástasis pulmonares precoces y tardías de fibrohistiocitoma maligno. Tratamiento quirúrgico
2009
Resumen El fibrohistiocitoma maligno (FHM) constituye la variante histologica del grupo de los sarcomas de partes blandas mas frecuente diagnosticada en el adulto. Es una neoplasia poco comun que se localiza, generalmente, en las extremidades inferiores. Son tumores agresivos, con gran tendencia a la recidiva local y a las metastasis sistemicas tardias. El pulmon y el higado son las localizaciones mas frecuentes. Presenta supervivencias cortas. La cirugia radical es el tratamiento de eleccion. Los pacientes con metastasis pulmonares se benefician de la cirugia. Actualmente la ablacion con radiofrecuencia (RFA) de las metastasis pulmonares es una opcion terapeutica en pacientes en los que la…
Contemporary Outcomes for the Curative Treatment of Colorectal Cancer Pulmonary Metastases.
2023
Purpose: Treatment of pulmonary metastases (PM) from colorectal cancer (CRC) is the standard of care by several guidelines from Europe and the USA, but the validity of this strategy has been recently questioned, and the available evidence supporting this strategy is weak. We report the outcomes of a curative intent strategy in a very recent and homogenous series of patients. Methods: We did a retrospective review of all curative intent surgical or ablative treatment of PM from CRC performed consecutively in 3 French institutions from January 2015 to December 2019. Demographics, clinicopathological, and molecular characteristics were evaluated. Cox regression models were used to identify pro…
Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer
2023
Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates located at sites of chronic inflammation and recognized as prognosticators in several cancers. We aimed to analyse the prognostic effect of TLSs in colorectal cancer (CRC) pulmonary metastases and primary tumours, with a comparison to the CD3+ and CD8+ cell density-based immune cell score (ICS). For TLS density and TLS maximum diameter analysis, 67 pulmonary metastases and 63 primary tumours were stained with haematoxylin and eosin. For ICS scoring and analysis, CD3 and CD8 immunohistochemistry was performed. Excellent interobserver agreement was achieved in all TLS measurements. Of all patients, 36 patients had low TLS den…